Rouiller Group
Research
- Follow this link to Associate Professor Isabelle Rouiller's Find an Expert page
- Please follow the link to Pubmed for current publications
Techniques
- Single particle cryo-EM and cryo-electron tomography.
Used equipment in the Facility for Electron Microscopy Research at McGill University in 2017: https://www.mcgill.ca/femr/
Will use EM facility in Bio21 in 2018:
http://www.bio21.unimelb.edu.au/advanced-microscopy.
- Classical EM (resin, immunogold…).
- Classic biochemical approaches.
Group Members
Group Leader
Assoc/Prof Isabelle Rouiller
Postdoctoral Fellows
Mohsen Kazemi
Sudipta Bhattacharyya
PhD Students
Sepideh Valimehr
Nazanin Mohebahi
Roopa Das
Martin Fleming
George Kobakhidze
Biography
Isabelle Rouiller trained as an Engineer in Biochemistry (INSA Lyon, France). She obtained a DEA (master equivalent) from INSA/ Université Claude Bernard Lyon on the study of mitochondria. She obtained a PhD in Virology/Cell Biology from the University of Hertfordshire (UK) in 1998 for research conducted at the Institute for Animal Health, Pirbright laboratories on the “Assembly of African Swine Fever Virus”. She undertook 2 postdoctoral posts at the Scripps Research Institute and at the Burnham Institute (San Diego, California, USA). She joined McGill University in 2007 first as an Assistant Professor and was later promoted to tenured Assistant Professor. In November 2017, she moved with her lab to the Bio21 Institute at the University of Melbourne as Associate Professor in the Department of Biochemistry and Molecular Biology.
Her research program is on structure-function studies of macromolecular complexes using cryo-EM with a focus on the function of ATPases (e.g. the AAA ATPase p97), membrane proteins involved in transport across membranes (e.g. anthrax toxins, ion channels, RND transporters) and viral glycoproteins involved in fusion (e.g influenza hemagglutinin). Her overall career objective is apply structural knowledge and her findings on how molecular machines function to improve public health.