New Super Resolution Microscopy Capability at Bio21 Institute

1 Aug 12

New Super Resolution Microscopy Capability at Bio21 Institute

Australian researchers are pioneering the application of new Super Resolution microscopy techniques to studies of important human pathogens such as the malaria parasite, as well as to understanding cancer and neurodegenerative diseases.  All with the help of the new OMX Blaze 3D-SIM microscope. 

A new addition to the Bio21 Institute’s suite of microscopy capabilities, the OMX BLAZE 3D-SIM is taking research to another level. 

Collaborators from Bio21 Institute, the University of Melbourne, Monash and La Trobe Universities and the Walter and Eliza Hall Institute (with co-funding from an ARC LIEF grant) have come together to bring one of the first OMX-BLAZE 3D SIM instruments in the world to the Bio21 Institute.

Officially opened in July, by Professor John Sedat, a leader of the consortium that developed the 3D-SIM super resolution microscope, the new OMX BLAZE provides researchers from across Victoria and nationally, the opportunity to delve deep into live cells.

The new OMX BLAZE achieves an 8-fold increase in volume resolution allowing researchers to see inside very small organisms such as bacteria and malaria parasites and inside the organelles of mammalian cells.

OMX Opening 2012

Pictured left to right: Professor Tony Bacic (Bio21 Institute Director), Professor Leann Tilley (Biochemistry and Molecular Biology), Dr Eric Hanssen (Bio21 EM Facility Manager), Professor John Sedat (University of California, San Francisco), Dr Paul McMillan (Biochemistry and Molecular Biology) and Professor Paul Gleeson (Head, Department of Biochemistry and Molecular Biology)

Dr Eric Hanssen is a Senior Research Fellow and Manager of the Bio21 Institute’s Microscopy Facility which is part of the broader University of Melbourne Advanced Microscopy Facility - bringing together multiple disciplines ranging from biochemistry to microbiology, anatomy and cell biology.

As part of the University of Melbourne's Advanced Microscopy Facility, state of the art electron and optical microscopes are located across multiple nodes at the Bio21 Institute, School of Botany, Department of Anatomy and Cell Biology, Department of Microbiology and Immunology, Department of Biochemistry and Molecular Biology and associated specialised light microscopy facilities located at the School of Chemistry, Chemical and Biomolecular Engineering and Florey Neuroscience Institute.

Instruments are available to research students, staff and the wider scientific community including government, business and industry users. 

Working alongside fellow microscopy experts, Dr Paul McMillan, Dr Sergey Rubanov and Dr Roger Curtain, a team of highly trained professionals with a wealth of experience in the examination and exploration of fine structure, with expertise in the fields of biology science, material science and micro-analysis, can provide advice and guidance on the applications of electron and light microscopy that best suit your needs.

Dr Eric Hanssen can be contacted for further information on the Bio21 Institute and the Advanced Microscopy Facility including the new OMX BLAZE Super Resolution microscope.



Helen Varnavas, 08 Aug 2012