Donnelly Group

"Our research focuses on the application of synthetic inorganic chemistry to biology, the role of transition metal ions in biology and the use of metal ions in chemical synthesis.” – Associate Professor Paul Donnelly

Research

The group focuses on the application of synthetic inorganic/organic chemistry to biology and materials science. In particular, we are interested in the application of coordination complexes as diagnostic or therapeutic agents. Our multidisciplinary research involves inorganic and organic synthesis followed by characterization utilizing a wide range of analytical techniques including: multinuclear NMR, electronic, and EPR spectroscopies, mass spectrometry, HPLC, electrochemical techniques and X-ray crystallography. Exploratory synthetic coordination chemistry and the design and isolation of new metal complexes underpins all of our research. Some projects aim to design new metal-based radiopharmaceuticals for diagnostic imaging and therapy of cancer. We also have programs aimed at developing new molecular agents for the diagnosis and treatment of neurodegenerative diseases including Alzheimer’s, Parkinson’s and Motor Neuron Disease. Other research in the group focuses on developing methods for bioconjugation of metal complexes to peptide, proteins and antibodies. We also have an interest in the use of metal complexes in organic synthesis. 

Techniques

Inorganic/organic synthesis, Schlenk lines for anaerobic preparative work, HPLC, UV-vis, electrochemistry, protein and antibody bioconjugations, peptide synthesis, NMR spectroscopy. 

Group Members

Group Head

Associate Professor Paul Donnelly

Postdoctoral Fellows and Research Assistants

Dr Timothy Connell

Dr David Hayne

Dr Asif Noor

Dr Andrea North

Nicholas Zia

Graduate Students

PhD students

Lachlan McInnes

Stacey Rudd

Masters/Honours Students

Scott Fletcher

HuiJing Koay

​Prea Maghami

Jake Rowan

Biography

Associate Professor Paul Donnelly
Associate Professor & Reader
School of Chemistry
T: (+613) 834 42399
E: pauld [at] unimelb.edu.au

Paul Donnelly is an Associate Professor and Reader, and ARC Future Fellow in the School of Chemistry. Paul is a graduate of the University of Western Australia and was a Post-doctoral Junior Research Fellow at the University of Oxford.