Seminar: "The membrane bound organization of blood coagulation Factor VIII" - Wednesday, 12.30 - 1.30pm, 18 Dec 2019

Wednesday, 18 December, 2019 - 12:30 to 13:30

What: CryoEM Seminar: 'The membrane bound organization of blood coagulation Factor VIII'

Who:  Svetla Stoilova-McPhie, Head of the CryoEM at the Center for Nanoscale Sciences, Harvard University

When: 12.30 - 1.30pm, Wednesday, 18 December 2019

Where: Bio21 Institute Auditorium, 30 Flemington Road, Parkville

Speaker Biography: Svetla Stoilova-McPhie, PhD

Graduated from the University of Sofia with Master in Biophysics (1986)

Received a Doctor of Philosophy degree from the Hungarian Academy of Sciences in Physics and Biophysics, following dissertation on the flash-photolysis of the opsin cycle of Bacteriorhodopsin. (1991)

Since 1992, Svetla work was dedicated on applying Cryo-Electron microscopy for structure determination of Macromolecular complexes through a series of postdoc and research fellowships in France (Strasbourg), the UK (Universities of Leeds, Warwick and Oxford and the United States (The Burnham Institute, San Diego(Ca), The Wadsworth Center, Albany (NY). During this time she was also the manager of the Cryo-EM facility at the University of Warwick, where she was also awarded a British Heart Foundation fellowship.

In 2008, Svetla was appointed as an Assistant Professor in Neuroscience and Cell Biology at the University of Texas Medical Branch at Galveston, where she continued her work on the membrane-bound organization of blood coagulation factor and complexes. She was awarded a National American Heart Association grant for her work.

In 2016, Svetla moved to the University of Texas Southwestern in Dallas and consecutively to the Center for Nanoscale Sciences at Harvard to develop methodologies and collaborate on high-resolution single -particle projects with the newly established 200 and 300 kV, FEG Cryo-EM microscopes equipped with autoloaders, energy filters, phase plates and direct electron detectors.

At present, Svetla is the advanced bio-imaging scientist, in charge of the Cryo-EM at the Center for Nanoscale Sciences, Harvard University. The focus of this position is to establishing a Single Particle Cryo-EM workflow and train undergraduate, graduate and postgraduate students in Cryo-EM of soft and biological materials. She is continuing her work on the coagulation factors following collaboration with the Harvard Medical School and the FDA (Food and Drugs Administration).

Svetla is a member of the Royal Microscopical Society since 1996, The European Microscopical Society and is at present the Biological Director of the North Eastern Society for Microscopy.